Abstract: Assessing the preparedness of Ghana's health sector is a crucial task that requires a comprehensive and multi-faceted approach. Ghana's health sector faces many challenges, including limited resources, inadequate infrastructure, and workforce shortages, which can impede the delivery of quality healthcare services to the population. Thus, building a strong health resilience system is essential to cope with catastrophic events, and the capacity to prepare and effectively respond to pandemics. The COVID-19 pandemic has highlighted the critical role of digital technologies in managing public health emergencies. In the context of long-term pandemic management, digital transformation can provide numerous benefits, such as improving the speed and efficiency of response, enhancing communication and collaboration, and enabling remote access to essential services. Empirically, our study found that individual and systemic resilience are significant predictors of long-term pandemic management. Conversely, community resilience in times of crisis is not a significant predictor.