Abstract: With the significant adverse impact of a pandemic like coronavirus disease 2019 (COVID-19) towards the teaching and learning experience, numerous educational institutions are looking for ways to improve their current practices and meet the challenges of this global threat. Despite the recommendations of applying Information and Communications Technologies (ICT) like video games to alleviate the negative effects of the pandemic, it is still not clear whether nursing teachers are willing to use it. Consequently, this study explored nursing teachers’ behavioral intention to employ mobile game-based learning (MGBL), and its relationship amongst core factors of the Theory of Planned Behavior (i.e., perceived behavioral control, subjective norms, and, attitude). Descriptive statistics revealed that most of the nursing teachers were female, a master’s degree holder, with an academic rank of instructor, not a licensed professional teacher, and a permanent and full-time employee at private institutions in the Visayas region of the Philippines. Moreover, they do not play mobile games and do not have an experience when it comes to MGBL. Lastly, Spearman’s correlation analysis revealed that Theory of Planned Behavior factors correlated positively with the intention of nursing teachers to use MGBL. This descriptive-exploratory study serves as a preliminary exploration of MGBL in nursing education and a future study will cover the prediction of nursing teachers’ intention to use MGBL in the classroom.